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Immune-Related Adverse Events in Advanced Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibition in Combination With Chemotherapy: A Brief Report

Published:November 25, 2022DOI:https://doi.org/10.1016/j.cllc.2022.11.006

      Clinical Practice Points

      • The occurrence of an immune related adverse event is prognostically useful in patients receiving immune checkpoint inhibitors in combination with chemotherapy.
      • Immune related adverse events occur at similar rates and have analogous toxicity profiles in patients receiving combination immune checkpoint inhibitors plus chemotherapy compared to patients receiving immune checkpoint inhibitor monotherapy.

      Keywords

      Abbreviations:

      ICIs (immune checkpoint inhibitors), NSCLC (non-small cell lung cancer), irAE (immune-related adverse event), ICI + CTX (immunotherapy and chemotherapy), OS (overall survival), HR (hazard ratio), PD-L1 (Programmed death ligand 1)
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